Paula Leandro is an Associate Professor at Faculty of Pharmacy, University of Lisboa.
She obtained her PhD in Biochemistry in 2001 and the Habilitation degree in Biochemistry in 2020.
Currently Paula Leandro is the coordinator of the research group “Metabolism, Genetics and Proteins in Health and Disease” from the Research Institute for Medicines (iMed.ULisboa).
Her research focuses on the study of misfolded variant proteins responsible for Inborn Metabolic Disorders (IMD), with a focus on Phenylketonuria, Classical Homocystinuria and Medium-chain Acyl-CoA Dehydrogenase Deficiency. She has been using biochemical and biophysical tools to characterise IMD variant proteins, to study the effect of small molecules on the rescue of protein conformation and to identify the mechanisms of protein stabilisation aiming to develop novel pharmacological therapies for IMD.
She has been involved in national and international research projects, both as Principal Investigator (PI) and Co-IP, and in the supervision of several Master and PhD students mainly in the field of IMD.