Dear Colleagues and Friends,

On behalf of the Organizing Committee, it is with great pleasure that we welcome you to the 22nd International Symposium of the Portuguese Society for Metabolic Disorders (SPDM).
This year´s programme will focus on “The Future of Inborn Errors of Metabolism: Decoding Complexity, Delivering Innovation”, with the aim of exploring recent therapeutic advancements and future perspectives in the field of Inherited Metabolic Disorders (IMD).
The Symposium programme has the privilege to count on the participation of outstanding experts from national IMD reference institutions, as well as several international experts, who will present you the most recent scientific advances in the main fields of IMD, including lysosomal storage disorders, mitochondrial diseases, amino acid catabolism disorders, and glycogen storage disorders. We will also have a pre-symposium course addressing emergencies in IMD and a special Masterclass session which will provide a broad and longitudinal overview on the topic of Phenylketonuria.
We hope that participants can get together in person, so important for exchange of ideas in an informal environment. The Vila Galé Hotel offers ideal conference conditions in a modern and pleasant atmosphere, located near the Mondego River and the historic center of Coimbra. This meeting has been made possible by the continued support of the sponsors, which we acknowledge. We are delighted to be hosting the 2026 SPDM Annual Symposium, hoping that it will be a success, and very much look forward to welcoming all of you in Coimbra.

João Durães and Sónia Moreira
Symposium Chairpersons