16th International SPDM Symposium
11th – 13th November 2020
Virtual Meeting
“New horizons in Inborn Errors of Metabolism”
Scientific Programme
| Wednesday, 11th November | |
| 15:00 16:30 |
Session I - Selected Free Communications Chairpersons: Ana M. Gaspar, Lisboa, PT | Hugo Rocha, Porto, PT |
| 16:30 17:30 |
Session II – Selected e-Posters Communications Chairpersons: Teresa Campos, Porto, PT | Margarida Silva, Lisboa, PT |
| 17:30 19:00 |
Session III - Selected free communications Chairpersons: Paula Garcia, Coimbra, PT | Anabela Bandeira, Porto, PT |
| Thursday, 12th November | |
| 08:15 08:30 |
Symposium Opening - Welcome Address on behalf of the SPDM Daniel C. Gomes – Symposium Chairperson |
| Session IV – Crosstalk amongst intracellular organelles Chairpersons: Isabel Tavares de Almeida, Lisboa, PT | Hugo Rocha, Porto, PT |
|
| 08:30 08:50 |
Fatty acid metabolism: intracellular interactions Ronald J. A. Wanders | Amsterdam, NL |
| 08:55 09:15 |
New perspectives in fatty acid disorders Ute Spiekerkoetter | Freiburg, DE |
| 09:20 09:40 |
Disorders of complex lipid metabolism Frédéric M. Vaz | Amsterdam, NL |
| 09:45 10:05 |
A clinical approach to complex lipid disorders Jean-Marie Saudubray | Paris, FR |
| 10:10 10:20 |
Session IV discussion |
| 10:20 10:50 |
Networking break |
| Session V – New insights in carbohydrate disorders Chairpersons: Elisa Leão Teles, Porto, PT | Patrícia Janeiro, Lisboa |
|
| 10:50 11:10 |
Glycogen storage disorders revisited René Santer | Hamburg, DE |
| 11:15 11:35 |
Update in disorders of galactose metabolism Estela Rubio-Gozalbo | Maastricht, NL |
| 11:40 11:50 |
Session V discussion |
| 11:50 12:50 |
Networking break |
| Session VI – New treatment perspectives Chairpersons: Domingo González-Lamuño, Santander, ES | Ana Paula Leandro, Lisboa , PT |
|
| 12:50 13:10 |
Enzyme substitution therapy: Pegvaliase for the treatment of PKU Ania Muntau | Hamburg, DE |
| 13:15 13:35 |
Expanding the use of substrate reduction therapy: nitisinone for the treatment of alkaptonuria Lakshminarayan Ranganath | Liverpool, UK |
| 13:40 14:00 |
Future directions in the treatment of lysosomal disorders Ans van der Ploeg | Rotterdam, NL |
| 14:05 14:15 |
Session VI discussion |
| 15:00 16:00 |
SPDM Nutrition Group meeting |
| Friday, 13th November | |
| Session VII – Expanding the concept of neurometabolic disorders Chairpersons: Sofia Duarte, Lisboa, PT | João Durães, Coimbra, PT |
|
| 08:30 08:50 |
Cellular neurometabolism: a tentative to connect cell biology and metabolism in neurology Angeles García-Cazorla | Barcelona, ES |
| 08:55 09:15 |
Neonatal Seizures: Are we there yet? Barbara Plecko | Graz, AT |
| 09:20 09:35 |
GOT2 deficiency: a novel malate-aspartate shuttle disease that leads to early-infantile encephalopathy (invited short communication) Rúben Ramos | New York, USA |
| 09:35 09:50 |
Mitochondrial bioenergetics in neurodegeneration (invited short communication) Vanessa Morais | Lisboa, PT |
| 09:50 10:00 |
Session VII discussion |
| 10:00 10:30 |
Networking break |
| Session VIII – Expanding treatment targets – what’s for the future of genetic therapy? Chairpersons: Dulce Quelhas, Porto, PT | Isabel Rivera, Lisbon, PT |
|
| 10:30 10:50 |
Recent advances in gene transfer therapy to the CNS in lysosomal storage diseases Nicolina Cristina Sorrentino | Naples, IT |
| 10:55 11:15 |
Emerging therapies in the hereditary porphyrias Jean-Charles Deybach | Paris, FR |
| 11:20 11:40 |
Emerging therapies for mitochondrial disease Shamima Rahman | London, UK |
| 11:45 12:00 |
Genetic substrate reduction therapy for mucopolysaccharidosis; Toward a sIRNA-containing nanoparticle targeted to brain cells (SPDM Aguinaldo Cabral Grant) Francisca Coutinho | Porto, PT |
| 12:00 12:10 |
Session VIII discussion |
| 12:10 13:10 |
Networking break |
| Session IX - Ageing in Inherited Metabolic Disorders Chairpersons: Anabela Oliveira, Lisboa, PT | Álvaro Hermida, Santiago de Compostela, ES |
|
| 13:10 13:30 |
Age related metabolic changes in Inherited Metabolic Disorders Fanny Mochel | Paris, FR |
| 13:35 13:55 |
Inborn metabolism defects in common neurodegenerative disorders Leonor Guedes | Lisboa, PT |
| 14:00 14:20 |
Ethical issues in the treatment of elderly patients Patrício Aguiar | Lisboa, PT |
| 14:25 14:35 |
Session IX discussion |
| 14:35 15:00 |
Awards / Closing Remarks M. Teresa Cardoso – Former SPDM President |
